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The Greco-Bactrian kingdom appeared in 250 BC, when the satrap Diodotos (or Theodotus in Latin) rebelled against his Seleucid ruler, Antiochos II, knowing that Antiochus was occupied in struggling against the Ptolemies in the west. At first Diodotos and his son Diodotos II conquered many territories southward in Ariana, restricting their conquests to Bactria. However around 230 BC, a local ruler named Euthydemos, maybe linked to the Seleucids, overthrew the Diodotids and created his own dynasty, extending his territory northward including Sogdiana and Ferghana. In 210 BC, the Seleucid Antiochos III fought victoriously against Euthydemos, forcing him to retreat, which led to a three-year siege of Bactra. This endless siege and the threat of the northern nomads forced Antiochos III to negotiate: He recognized Euthydemos as king and gave him one of his daughters in exchange of supplies and war elephants.
Having the West front secured, the Greco-Bactrian kings waged war against their eastward neighbors, taking advantage of the decline of the Mauryan dynasty. In less than 20 years, under Demetrios and his descendants, they took the Paropamisadaes, Arachosia, Gandhara and Western Punjab. In the same time the central power was divided between several kings which seemed not be always in good terms. Some of them ruled only eastward of the Hindukush, being the first Indo-Greek kings.
In 171 BC Eucratides, who may also have been linked to the Seleucids, overthrew the Greco-Bactrian king and waged war against the Indo-Greek ones. He was successful at first until an Euthydemid called Menander forced him to retreat west of the Hindu-Kush in Bactria. This marked the beginning of the rivalry between Euthydemids and Eucratids, which lasted for a long time. This rivalry weakened the Greco-Bactrian kingdom: Sogdiana was soon lost, and Eucratids was forced to abandon western Bactria to Parthian kings. In 145 BC, Eucratides was murdered by his own son, which led a period of politic instability resulting in the overthrow of the last Indo-Greek king, Heliokles, in 130 BC by the Yuezhei nomads.
The Greco-Bactrian kingdom had a unique place in Greek imagination, being a Hellenistic kingdom at the border of the known world. This kingdom had frequent contacts with Indian and nomad neighbors, and possibly also the Chinese, which is evident in the spread of their goods and coins. The Greco-Bactrian art was known to be one of the finest at this time, as the statues found at Ostobora (modern Aï Khanoum) and Bactra attest, and their coins were of particularly high quality. This originality was not lost with the fall of the last Greco-Bactrian king, because some continuations of Greco-Bactrian art is evident in their Yuezhei and Koushan successors.
Having the West front secured, the Greco-Bactrian kings waged war against their eastward neighbors, taking advantage of the decline of the Mauryan dynasty. In less than 20 years, under Demetrios and his descendants, they took the Paropamisadaes, Arachosia, Gandhara and Western Punjab. In the same time the central power was divided between several kings which seemed not be always in good terms. Some of them ruled only eastward of the Hindukush, being the first Indo-Greek kings.
In 171 BC Eucratides, who may also have been linked to the Seleucids, overthrew the Greco-Bactrian king and waged war against the Indo-Greek ones. He was successful at first until an Euthydemid called Menander forced him to retreat west of the Hindu-Kush in Bactria. This marked the beginning of the rivalry between Euthydemids and Eucratids, which lasted for a long time. This rivalry weakened the Greco-Bactrian kingdom: Sogdiana was soon lost, and Eucratids was forced to abandon western Bactria to Parthian kings. In 145 BC, Eucratides was murdered by his own son, which led a period of politic instability resulting in the overthrow of the last Indo-Greek king, Heliokles, in 130 BC by the Yuezhei nomads.
The Greco-Bactrian kingdom had a unique place in Greek imagination, being a Hellenistic kingdom at the border of the known world. This kingdom had frequent contacts with Indian and nomad neighbors, and possibly also the Chinese, which is evident in the spread of their goods and coins. The Greco-Bactrian art was known to be one of the finest at this time, as the statues found at Ostobora (modern Aï Khanoum) and Bactra attest, and their coins were of particularly high quality. This originality was not lost with the fall of the last Greco-Bactrian king, because some continuations of Greco-Bactrian art is evident in their Yuezhei and Koushan successors.
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Cyrus the Great (558-530 BC) built the first universal empire, stretching from Greece to the Indus River. This was the famous Achaemenid Dynasty of Persia. An inscription at Naqsh-i-Rustam, the tomb of his able successor Darius I (521-486 BC), near Persepolis, records Gadara (Gandhara) along with Hindush...
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Ai Khanum (also spelled Ai-Khanoum or Ay-Khanum, lit. “Lady Moon” in Uzbek), was founded in the 4th century BC, following the conquests of Alexander the Great and was one of the primary cities of the Greco-Bactrian kingdom. The site is located in the northern part of modern Afghanistan...
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Warning: See the definitions of Greco-Bactrian and Indo-Greek Kingdoms before reading this article, otherwise the following lines could give you serious headaches! A lack of information is a common problem for historians of the Greco-Bactrian and Indo-Greek kingdoms, due to the almost-inexistence...
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The rarity of the appearance of Greco-Bactrian and Indo-Greek kingdoms in ancient literature is one of the reasons why those states are so little-known today. Indo-Greek literature did exist, but none has been found that speaks about the Greco-Bactrian and Indo-Greek states. Classical authors tell...
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- Sparta: Hellenistic Bactria: Features of the independent political development on the eastern outskirts of the Greco-Macedonian world
http://www.sparta.markoulakispublications.org.uk/index.php?id=294
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Timeline
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250 BCFormer satrap Diodotos rebels against Seleucid king Antiochos I, creating the Greco-Bactrian kingdom.
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c. 230 BCDiodotos II is overthrown by Euthydemos. Beginning of the Euthydemid dynasty.
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208 BCSeleucid king Antiochos III wins the battle of the Arius river against Euthydemos.
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208 BC - 206 BCSiege of Bactra by Antiochos III.
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206 BC
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c. 200 BC
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c. 190 BCFirst appearance of multiple Euthydemid kings at the same time. Beginning of the Indo-Greek kingdoms.
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171 BCIn odrer to show the break of dynasty, Eucratides begin a new Yona (or Greek) era.
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c. 155 BCThe Euthydemid Menander succeeds to push back the Eucratids westward of the Hindu-Kush.
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145 BCMurder of Eucratides by his son. Weakening of the Greco-Bactrian kingdom.
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c. 130 BCThe Yuezhei take control of Bactria.

Dr. Ranajit Pal wrote on 04 October 2011 at 02:15:
I have written in a paper published in the journal Scholia (vol. 15) that Diodotus-I was the great Asoka, but sadly this is not taken into account in this article. The paper is also available at
http://ranajitpal-jesus-from-asia-minor.blogspot.com/